Ibogaine therapy for PTSD, CPTSD and trauma healing at MindScape Retreat
MindScape Retreat
Trauma Recovery. Cozumel, Mexico

Ibogaine Treatment for
PTSD, CPTSD & TBI

Ibogaine is the only plant medicine currently demonstrated to address the neurochemical and emotional roots of PTSD, Complex PTSD, and Traumatic Brain Injury. not merely manage their symptoms.

Speak With Our Medical Team
98.6%
Clinical PTSD Resolution
PCL-5 below threshold at 6 months (n=73)
900+
Guests treated since 2019
Veterans, survivors, civilians
24/7
Physician supervision on-site
Board-certified medical staff
DA
Medically reviewed by Dr. Arellano, M.D.
Medical Director, MindScape Retreat · Board-certified physician specializing in ibogaine-assisted detoxification with over 900 patients treated.

Understanding the Conditions

The Neurological Reality of Trauma

Post-Traumatic Stress Disorder (PTSD) and Complex PTSD (CPTSD) are severe mental health conditions triggered by experiencing or witnessing traumatic events. While PTSD arises from a single traumatic incident, CPTSD results from prolonged exposure to trauma. often in contexts where the individual felt trapped, such as in cases of chronic abuse, combat, or captivity. These conditions produce debilitating symptoms including flashbacks, severe anxiety, depression, emotional dysregulation, and a profound sense of detachment from reality.

Traumatic Brain Injury (TBI) adds another dimension: direct structural and neurochemical damage to the brain tissue itself. Inflammation, disrupted neurotransmitter signaling, and impaired neuroplasticity compound the psychological impact of trauma. Traditional treatments such as SSRIs and talk therapy often provide only partial relief, leaving the underlying neurological damage unaddressed and the trauma unresolved at its root.

Conditions We Treat

Trauma, TBI, and Related Mental Health Conditions

PTSD. Single-Incident Trauma

Whether from combat, assault, accident, or medical trauma, PTSD arising from a single event responds powerfully to ibogaine's ability to facilitate the processing and integration of traumatic memory. transforming it from an active wound into resolved history.

Complex PTSD. Chronic Trauma

CPTSD from prolonged abuse, neglect, or captivity involves deep identity-level disruptions that single-incident treatments rarely address. Ibogaine's capacity for extended introspective processing gives CPTSD patients access to psychological territory that years of conventional therapy often cannot reach.

Traumatic Brain Injury (TBI)

Ibogaine's upregulation of GDNF and activation of the sigma-2 receptor promotes neuroregeneration and reduces neuroinflammation. two of the central physiological challenges in TBI recovery. Many TBI patients report meaningful cognitive and emotional improvements following treatment.

Military & First Responder Trauma

Veterans and first responders carry a particular burden: moral injury, operational stress, and traumatic memory layered upon each other across years of service. Ibogaine addresses all of these simultaneously, offering a depth of processing that medication management alone cannot provide.

The Mechanism

How Ibogaine Heals Trauma at the Neurological Level

Ibogaine's efficacy in treating PTSD and related conditions is rooted in its interaction with the brain's neurochemical pathways. The upregulation of GDNF supports the survival of dopaminergic neurons and promotes neuroplasticity. the brain's ability to reorganize itself by forming new neural connections. By enhancing GDNF levels, ibogaine supports the repair of neural circuits damaged by trauma, facilitating restoration of cognitive function and emotional balance.

Noribogaine. ibogaine's active metabolite. remains in the body for several months post-treatment, binding to the serotonin transporter, sigma-2 receptor, and kappa-opioid receptor. It inhibits serotonin reuptake to improve mood, activates the sigma-2 receptor for neuroprotective and anti-depressive effects, and modulates the kappa-opioid receptor to reduce stress and anxiety without addictive potential. Unlike SSRIs that temporarily increase serotonin, ibogaine promotes a more balanced and sustained enhancement of serotonin signaling. We integrate NAD+ infusions and 5-MeO-DMT alongside ibogaine to further amplify neuroplasticity and deep healing.

MindScape's 14-day trauma protocol incorporates twice-daily ibogaine TA booster doses across multiple consecutive days before the HCl flood session. This extended neurotrophic priming phase initiates BDNF and GDNF upregulation days before the flood dose amplifies both pathways, opening a substantially wider neuroplastic window for trauma processing and neural repair. For TBI patients specifically, early GDNF elevation begins reducing neuroinflammation and supporting oligodendrocyte function before the primary session. The graduated dosing also stabilizes autonomic nervous system function — particularly heart rate variability — which is critical when patients carry trauma-conditioned hyperarousal that would otherwise complicate the emotionally intense flood experience.

Clinical Protocol

The MindScape Treatment Journey

01

Free Consultation

Our care team listens first. We learn your trauma history, current medications, prior treatments, and what relief has looked like. and what it has not. This conversation is confidential and carries no obligation.

02

Medical Screening

Full medical intake including EKG cardiac evaluation, complete bloodwork, and liver panel. Patients on SSRIs or other psychiatric medications are guided through a medically supervised taper prior to treatment to ensure safety.

03

Personalized Protocol Design

Our medical director and psychologists design your protocol based on your specific conditions. PTSD, CPTSD, TBI, or combinations. calibrating ibogaine dosing, supplemental NAD+, and the inclusion of 5-MeO-DMT as clinically appropriate.

04

Treatment in Cozumel

The ibogaine session unfolds over 12 to 24 hours under continuous physician supervision at our Cozumel retreat. Many guests describe encountering and processing core traumatic memories during the experience in ways that feel complete rather than re-traumatizing.

05

Integration & Aftercare

Trauma integration requires time and structure. Our team provides post-treatment support, 90-day integration framework, scheduled coaching, and access to our patient community. ensuring the gains from treatment are consolidated and sustained.

Common Questions

PTSD, CPTSD & TBI. Frequently Asked Questions

This is one of the most important distinctions between ibogaine and conventional trauma therapies. During the ibogaine experience, many guests encounter traumatic memories in a state that feels observational rather than reactive. as though viewing the experience from a place of calm distance rather than being inside it. Researchers believe this is related to ibogaine's modulation of the default mode network and its dissociative properties at therapeutic doses. Our clinical team is present throughout the session and conducts integration work afterward to support healthy processing of whatever arises.

Both. For TBI patients, ibogaine's neurogenic and neuroprotective properties are particularly relevant: GDNF upregulation supports the repair of damaged neural circuits, and noribogaine's activation of the sigma-2 receptor has been associated with reduced neuroinflammation and neural regeneration. Many TBI patients report cognitive improvements. clearer thinking, reduced brain fog, improved emotional regulation. alongside the psychological benefits. We screen TBI patients carefully given the neurological complexity involved.

Ibogaine has shown particularly striking results in veterans with treatment-resistant PTSD, including several published case series and observational studies from military populations. Veterans with combat PTSD often carry moral injury and complex grief alongside the acute trauma symptoms. dimensions that conventional SSRI treatment does not address. Ibogaine's capacity to facilitate deep introspective processing of moral and existential aspects of combat experience is one reason it resonates strongly with this population. We welcome veterans and have treated guests from multiple military branches.

PTSD arising from a single incident typically involves a more defined traumatic memory structure, and the ibogaine experience often centers on processing that specific event. CPTSD from prolonged trauma involves layered identity disruptions, attachment wounds, and a more diffuse psychological presentation. Our protocols are individualized: CPTSD patients often benefit from a more extended preparation process, a carefully calibrated dose that allows depth without overwhelm, and more intensive post-treatment integration support. Our psychologists specialize in both.

Patients currently taking SSRIs, SNRIs, benzodiazepines, or other psychiatric medications require a medically supervised taper before ibogaine therapy. The timeline varies significantly depending on the specific medication and dosage. typically 2 to 6 weeks. Our medical team provides a full taper protocol as part of pre-treatment preparation. This is not something to attempt independently; we guide the entire process.

Cozumel Island is consistently rated among Mexico's safest destinations for international visitors. a distinct environment from the mainland areas near Cancun and Tulum. The island has a long history of medical tourism, international diving, and retreat-based wellness. MindScape Retreat guests travel from across North America, Europe, and beyond. We coordinate airport transfers from Cancun International through Cozumel ferry, and our team supports every logistical aspect of your arrival.

Program Investment

All-Inclusive Retreat Pricing

Psilocybin Program

$4,000

5-day, 4-night psilocybin-assisted therapy retreat. All-inclusive with island excursions.

Ibogaine Protocol

$7,500

7 day all-inclusive ibogaine program. Full trauma processing and neurological support.

All pricing includes accommodations, meals, medical supervision, pre-treatment preparation, NAD+ infusions, and 90-day integration support. No hidden fees.

Begin Healing

Trauma Does Not Have to Define the Rest of Your Life

Our medical team will review your history honestly and tell you whether ibogaine treatment is appropriate for your specific situation. The conversation is confidential and carries no obligation.

Request a Confidential Consultation

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